Abantu babheka i-oxide nanoenzymes njengezinto ezifanele kakhulu zokuvuselela ukulinganisa ukwelashwa kwe-oxidative stress-mediated pathophysiological disorders ngama-enzyme e-antioxidant, kodwa umsebenzi we-catalytic we-oxide nanoenzymes awukagculisi.
Ngenxa yalokhu, u-Tang Zhiyong, u-Wang Hao, u-Xingxin Fa, u-Qiao Zengying, nabanye abavela e-National Nanometer Centre babike okokuqala ukuthi kunezingqimba ezincane kakhulu.CeO2nge-intrinsic stress isetshenziselwa ukumelana ne-nano oxidation.
Amaphuzu abalulekile alesi sihloko
Iphuzu eliyisihluthulelo 1. Ngokubala kwethiyori nokuhlaziya, kwatholakala ukuthi ukucindezeleka okungaphezulu kweCeO2ihlobene nokungafinyeleli kahle kokuxhumana kwe-Ce kanye nobukhulu beCeO2.Ngakho-ke, ama-nanosheet azacile kakhulu anogqinsi lwe-~1.2 nm ahlanganiswa, futhi ukucindezeleka okungaphakathi kwendiza/ngaphandle kokucindezeleka kwendiza kufinyelele ~ 3.0% kanye ~ 10.0%, ngokulandelana.
Iphuzu eliyisihluthulelo 2. Uma kuqhathaniswa nama-nanocubes, le-ultra-thin nanosheet Ce-O chemical bond iye yathuthukisa i-covalence, okuholela ekukhuleni kwe-2.6 kokuphindaphinda komsebenzi we-catalytic we-SOD (superoxide dismutase) kanye nokunyuka okuphelele kwe-2.5 komthamo we-antioxidant.Ukusebenzisa lokhu kuzacile kakhuluCeO2ifilimu enengcindezi yangaphakathi yokwelapha i-ischemic stroke in vivo inokusebenza okungcono kunemithi yokwelapha yendabuko
Isikhathi sokuthumela: Sep-08-2023