Iziguli zezinso ezingapheli (CKD) zivame ukuba ne-hyperphosphatemia, futhi i-hyperphosphatemia ende ingaholela ezinkingeni ezinkulu ezinjenge-hyperparathyroidialism ye-renal, renal osteodstrophy, kanye nesifo senhliziyo. Ukulawula amazinga we-Phosphorus kuyingxenye ebalulekile yokuphathwa kweziguli ze-CKD, kanye nama-phosphate ama-phosphone izidakamizwa zegumbi zokwelashwa kwe-hyperphosphatemia ekwelapheni. Eminyakeni yakamuva,I-Lanthanum Carbonate, njengohlobo olusha lwe-con-calcium ne-non-aluminium phosphate Binder, kancane kancane ungene emkhakheni wabantu we-Vision futhi uqale "umncintiswano" onamabhasi endabuko we-phosphate.
"Ama-vides" kanye "nokwehlisa" kwezibopho zendabuko ze-phosphate
Ama-mosphate ama-phosphate ama-beinders ikakhulukazi afaka ama-phosphate ama-phosphate ama-phosphate ama-phosphate (njenge-calcium carbonate ne-calcium acetate) kanye nama-aluminium-aqukethe ama-phosphate ama-phosphate ama-phosphate (afana ne-aluminium hydroxide). Bahlangana nama-phosphates ekudleni ukuze bakha amakhompiyutha we-insoluble, ngaleyo ndlela kunciphise ukumuncwa kwamathumbu kwe-phosphorus.
I-calcium equkethe ama-phosphate ama-phosphate
I-Aluminium-equkethe ama-phosphorus ama-phosphorus ama-phosphorus: Umphumela we-phosphorus oqinile, kepha ukunqwabelana kwe-aluminium kunobuthi kakhulu futhi kungadala isifo samathambo esihlobene ne-aluminium kanye ne-encephalopathy, futhi okwamanje asisetshenziswa kancane.
I-Lanthanum Carbonate: Ukukhuphuka okusha, ngezinzuzo ezivelele
ILanthanum Carbonate iyi-carbonate ye-rare ndral metal element lanthanum, enomshini ohlukile wokubopha. Ikhipha ama-lanthanum ion kwimvelo ye-acidic ye-Digery Tract kanye nokwakha amafomu kakhulu i-lanthanum phosphate nge-phosphate, ngaleyo ndlela ivimbele ukumuncwa kwe-phosphorus.
Ukwethulwa okufushane kweLanthanum Carbonate
| Igama lomkhiqizo | I-Lanthanum Carbonate |
| Uhlobo | La2 (CO3) 3.XH2O |
| Case No. | 6487-39-4-4 |
| Isisindo molecular | 457.85 (anhy) |
| Incekusana | 2.6 g / cm3 |
| Iphuzu elincibilikayo | N / a |
| Ukubonakala | I-White Crystal Powder |
| Ubuhlakaniselo | Incibilike emanzini, ngokulinganayo incibilika kuma-acid amaminerali aqinile |
| Qinisa | I-hygroscopic kalula |
Uma kuqhathaniswa nama-phosphorus ama-phosphorus afinders, iLanthanum Carbonate inezinzuzo ezilandelayo:
Ayikho i-calcium ne-aluminium, ukuphepha okuphezulu: kugwema ubungozi be-hypercalcemia ne-alumininum ubuthi, ikakhulukazi iziguli zokwelashwa isikhathi eside kanye nengozi yokubalwa kwemivimbo.
Ikhono elinamandla le-phosphorus elibophayo, umphumela wokunciphisa i-phosphorus obalulekile
I-reakression embalwa ye-gasttrograster embi, ukuhambisana okuhle kwesiguli: I-lanthanum carbonate okuthandayo, kulula ukuyithatha, kunokucasuka okuncane kwesisu, futhi iziguli kungenzeka zinamathele ekwelashweni kwesikhathi eside.
Ubufakazi Bokucwaninga Ngomtholampilo: ILanthanum Carbonate yenza kahle
Izifundo eziningi zemitholampilo zikuqinisekisile ukusebenza nokuphepha kwe-lanthanum carbonate ezigulini ze-CKD. Ucwaningo luye lwabonisa ukuthi iLanthanum Carbonate ayiphansi noma iphakeme kakhulu kunendabuko yendabuko ye-phosphate ekunciphiseni amazinga we-phosphorus egazi, futhi angakwazi ukulawula ngempumelelo amazinga we-Ipth futhi athuthukise izinkomba ze-IPone Metabolism. Ngaphezu kwalokho, ukuphepha kokwelashwa kwesikhathi eside ngeLanthanum Carbonate kuhle, futhi akukho kuqongelela okusobala kweLanthanum kanye nokuphendula okunobuthi sekutholakele.
Ukwelashwa komuntu ngamunye: Khetha uhlelo oluhle kakhulu lwesiguli
Yize iLanthanum Carbonate inezinzuzo eziningi, akusho ukuthi ingashintsha ngokuphelele ama-phosphate ama-linders. Umuthi ngamunye unezinkomba zawo kanye nokuphambana, futhi uhlelo lokwelashwa kufanele lube khona ngokwasesimweni esithile sesiguli.
ILanthanum Carbonate ilungele kakhulu lezi ziguli ezilandelayo:
Iziguli ezine-hypercalcemia noma ingozi ye-hypercalcemia
Iziguli ezinamava ama-vascular noma ubungozi bokubalwa kwemivimbo
Iziguli ezinokungabekezeleli kahle noma ukusebenza kabi kwezibopho zendabuko phosphate
Ama-beinders endabuko we-phosphate asakwazi ukusetshenziselwa iziguli ezilandelayo:
Iziguli ezinezimo zomnotho ezilinganiselwe
Iziguli ezingalwazi noma zingabekezeleli i-lanthanum carbonate
Ukubheka esikhathini esizayo: ILanthanum Carbonate inekusasa eliqhakazile
Ngokujula kocwaningo lwemitholampilo kanye nokuqongelelwa kwesipiliyoni somtholampilo, isimo se-lanthanum carbonatemia ekwelapheni i-hyperphosphatemia ezigulini ze-CKD kuzoqhubeka nokwenza ngcono. Esikhathini esizayo, kulindeleke ukuthi i-lanthanum carbonate kulindeleke ukuthi ibe yi-ly-line shosphate mbinder, ilethe izindaba ezinhle kwiziguli eziningi ze-CKD.
Isikhathi sePosi: Mar-25-2025